Cancer incidence & progression Vitamin d status.

[tedhutchinson]

Originally Posted by oscar

I was thinking more of Pete but I'll check the health shop for it thanks Odie.

UK health shops only sell 1000iu at best. As I have explained previously theaverage UK adult has a 25(OH)D status around 35nmol/l this time of year. 1000iu raises that to 55nmol/l and thus anyone only using 1000iu/daily remains deficient.

To get the best protection from cancer heart disease diabetes, ms etc you need to achieve 150nmol/l and that is why I insist simple maths tell us that around 5000iu/daily is needed.

For a child you can work on the basis of 1000iu per 25lbs.
If you're overweight then maybe you also need to use that formula.

It's probable that if you currently have an inflammatory condition or are overweight then you will almost certainly need more than I've stated. But using the 5000iu/daily to start with and getting tested at 3 months should indicate how much extra you require.

[tedhutchinson]

Originally Posted by oscar

What do you suggest for some-one with cancer?

Read how Vitamin d may be helpful in slowing cancer progression when used in EFFECTIVE amounts.


This article explains what is needed. The important fact you need to grasp is that most cancers progress faster in the winter than the summer so keeping your Vitamin d status at the peak summer level thoughout the year keeps progression as slow as possible.

Remember to that cancers feed on sugar so cutting out carbohydrates of all kinds but particularly refined fast acting carbs and fructose, will help starve the cancer.

[Sunshine]

Is there such a thing as too much Vit. D? Any side affect to expect?

[tedhutchinson]

Originally Posted by Sunshine

Is there such a thing as too much Vit. D? Any side affect to expect?

Yes but you really don't have to worry about it.
D3 cholecalciferol is the NATURAL form of the vitamin, unlike the prescribed synthetic form D2 ergocalciferol.
There are reports of adverse events using D2 but they need not concern us as no one here would be daft enough to use prescription vitamin d.

D3 is an inert substance and on it's own has no impact whatsoever. It requires 2 hydroxylations before it becomes activated and those hydroxylations only occur if your vitamin d receptor cells require it. The vitamin d3 molecule is biologically identical to the substance your skin makes itself so as your skin could, given full body prone exposure in summer, make 50,000u/daily that is an absolutely safe amount to take occassionally. For regular use 10.000iu daily is a safe upper limit.

In practice Dr Davis finds 5000iu/daily sufficient for most women at latitude 43 and 6000iu for men. At those levels no one can is likely to get above 80ng 200nmol/l.
It generally takes 40,000iu daily for many months to get anywhere near the levels associated with adverse events.

Using 5000~6000iu/daily it will take at least 90 days to replete the system so don't expect to feel the benefit for some time. The problem is that your body actually likes to use around 5000iu daily so the build up in status is coming from sun and diet and not the daily supplement which is only covering your basic daily needs. It's a bit like trying to fill the bath without a plug.
If you needed to speed up the repletion then 50,000iu D3 capsules are available and ONE of these each week for EIGHT weeks only should help. That way you average 7000iu daily, 2000iu/d more than your body actually needs so the the vitamin d3 bath fills faster than your using it.

[Sunshine]

Thanks. I may just visit my health food store and give it a try. Not a lot of restorative sunshine in my parts in the winter.

[oscar]

Originally Posted by tedhutchinson

Read how Vitamin d may be helpful in slowing cancer progression when used in EFFECTIVE amounts.


This article explains what is needed. The important fact you need to grasp is that most cancers progress faster in the winter than the summer so keeping your Vitamin d status at the peak summer level thoughout the year keeps progression as slow as possible.

Remember to that cancers feed on sugar so cutting out carbohydrates of all kinds but particularly refined fast acting carbs and fructose, will help starve the cancer.

Prostate cancer feeds on Testosterone..... Once that is depleted, it spreads. My husband was 8 on the 'Gleason scale' before he had surgery. The scale is why he was given 75% chance the cancer would re-appear as it now has. 8 comes into the catagory of most agressive and cells are extremely difficult to eradicate.
We are now waiting for a scan to see if the re-appearence has spread as it did at an alrming rate prior. I'm sorry to sound dis-missive but an 8 on the 'Gleason scale' is very difficult to halt what ever drug or vitimin is used.

[tedhutchinson]

Originally Posted by Sunshine

Thanks. I may just visit my health food store and give it a try. Not a lot of restorative sunshine in my parts in the winter.

You may find the Online retailers cheaper. I use IHERB now code WAB666 saves you $5. and $8.80 for 120 isn't a bad price.
Dr Davis finds the solid tablets don't work reliably. Although I didn't have any problems absorbing these dry powder capsules I can understand why people who don't eat breakfast and want to take their tablets in the morning may have problems when their is no fat to absorb the vitamin d3 (it's fat soluble)
You can also find Vitamin D drops that are easily incorporated into your meals. foods.
however I generally go for the cheapest form that I know works.

[tedhutchinson]

Originally Posted by oscar

Prostate cancer feeds on Testosterone..... Once that is depleted, it spreads. My husband was 8 on the 'Gleason scale' before he had surgery. The scale is why he was given 75% chance the cancer would re-appear as it now has. 8 comes into the catagory of most agressive and cells are extremely difficult to eradicate.
We are now waiting for a scan to see if the re-appearence has spread as it did at an alrming rate prior. I'm sorry to sound dis-missive but an 8 on the 'Gleason scale' is very difficult to halt what ever drug or vitimin is used.

Indeed but as we know that higher 25(OH)D status is associated with the best prognosis what have you to lose except the few cents daily an effective strength D3 capsules costs.

If my property was on fire I would want my local fire brigade to attend complete with effective amounts of anti inflammatory agent. I would be pretty annoyed if they arrived without sufficient fire retardants to apply at maximum power or efficiency needed. The hormone Calcitriol can only operate to damp down inflammation in your body at MAXIMUM VELOCITY when there is available an equal amount of D3 molecules to match the circulating Calcidiol molecules.

Your body only stores D3 in significant amounts above 125nmol/l ~ 50ng/mL so if you want your internal fire brigade to operate at maximum efficiency anything under that level means it is underfunctioning . Ideally 60ng or 150nmol/l is safer as it gives a bigger reserve for emergency use.

I'd say you were in an emergency scenario and I cannot understand why anyone in such a situation fails to take appropriate action.

So I presume if your car suffered an accident because the tyres were under inflated you would say, "Well this car is now pretty badly damaged, it's almost a right off so there is no point in pumping the tyres up ever again, we'll just wait until another worse accident occurs and then claim on the insurance."

[oscar]

Originally Posted by tedhutchinson

Indeed but as we know that higher 25(OH)D status is associated with the best prognosis what have you to lose except the few cents daily an effective strength D3 capsules costs.

If my property was on fire I would want my local fire brigade to attend complete with effective amounts of anti inflammatory agent. I would be pretty annoyed if they arrived without sufficient fire retardants to apply at maximum power or efficiency needed. The hormone Calcitriol can only operate to damp down inflammation in your body at MAXIMUM VELOCITY when there is available an equal amount of D3 molecules to match the circulating Calcidiol molecules.

Your body only stores D3 in significant amounts above 125nmol/l ~ 50ng/mL so if you want your internal fire brigade to operate at maximum efficiency anything under that level means it is underfunctioning . Ideally 60ng or 150nmol/l is safer as it gives a bigger reserve for emergency use.

I'd say you were in an emergency scenario and I cannot understand why anyone in such a situation fails to take appropriate action.

So I presume if your car suffered an accident because the tyres were under inflated you would say, "Well this car is now pretty badly damaged, it's almost a right off so there is no point in pumping the tyres up ever again, we'll just wait until another worse accident occurs and then claim on the insurance."

I hardly equate that to the illness that my husband is suffering and if i were honest, I'd say a little insulting.
Two years ago, my husband was given 9 months to live without radical open surgery. Prostate cancer is silent. There are very few symptoms. By the time most men notice symptoms, it is too late and the cancer has spread. There was only one thing that saved my husbands life and that was a damn good surgeon and the best health care he could ask for.
Now the cancer has returned, perhaps you can explain to me, how your vitimin is not used by Oncology?

[tedhutchinson]

Originally Posted by oscar

I hardly equate that to the illness that my husband is suffering and if i were honest, I'd say a little insulting.
Two years ago, my husband was given 9 months to live without radical open surgery. Prostate cancer is silent. There are very few symptoms. By the time most men notice symptoms, it is too late and the cancer has spread. There was only one thing that saved my husbands life and that was a damn good surgeon and the best health care he could ask for.
Now the cancer has returned, perhaps you can explain to me, how your vitimin is not used by Oncology?

there is absolutely no profit in using Vitamin D3. It is made from the biproducts of the wool and fish processing industries and is not patentable.
You will see if you study pubmed that they are trying to make patentable analogues of vitamin d so they can make a profit from it but while until then they will studiously ignore the fact that people diagnosed treated when 25(OH)D status is high have a better prognosis than those diagnosed/treated when D3 status is low.

I can't see what you have to lose, apart from the few $ effective strength 5000iu D3 costs?
If I were in your shoes I'd leave no stone unturned.